Welcome to Moffitt Cancer Center
 
Department of Cancer Imaging and Metabolism

The Department of Cancer Imaging and Metabolism was initiated in April 2008 with the hiring of Drs. Robert A. Gatenby and Robert J. Gillies as chair and vice-chair of Radiology. 

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Research Projects

Targeting agents and nanomedicine:

Targeting agents and nanomedicine is coordinated by Dave Morse, PhD. It meets on Tuesdays from 4-6 pm in PI-2, as well as by telecon with University of Arizona on Mondays from 4-6. Members include Liping Xu, Amanda Shanks Huynh, Natalie Barkey, Prasanta Dutta, Narges Tafreshi and Kamini Sewda. It is funded by two NIH grants: an R01 in Pancreatic Cancer and an R01 in melanoma; a UF-Moffitt consortium grant in breast cancer with PERC, and a Bankhead-Coley melanoma pre-SPORE grant in collaboration with Intezyne.

The goal of this theme is to develop agents that are specifically targeted to cancer cell surface epitopes for the purpose of delivering imaging contrast and/or therapy. This work depends on: (1) the availability of useful gene expression data and tissue arrays that are used to identify targets; (2) the availability of synthetic chemistry and screens to develop ligands for these agents; and (3) the availability of chemistries to deliver imaging contrast agents or therapeutic payloads. Since coming to Moffitt, this theme has expanded from linear multivalent ligands to also include nanoparticles for therapy and imaging. In this theme, collaborations have been initiated with the Particle Engineering Research Center, PERC, at UF; Intezyne and the nanotechnology center of excellence at USF.Go back


Latest Group News  View Alll

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3/5/2014: Jasmine Oliver was selected to participate in the 64th Lindau Nobel Laureate Meeting dedicated to Physiology or Medicine, in Lindau Germany from June 29th - July 4th this summer.



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11/2012: The Radiomics Workshop report 2012 is available[View]



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Abstract accepted for WMIC 2012: Characterization of Multivalent Targeted Molecular Imaging Probes



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Allison Cohen's abstract accepted for WMIC 2012: Discovery of Cell-Surface Markers for Molecular Imaging of Lung Cancer